Endocrine Abstracts

Backgroud and Aim: Gastrointestinal (GI) symptoms are reportedly common in diabetes mellitus (DM) with a conflicting data on its prevalence in this specific population. The aim of our study is to determine the prevalence of GI symptoms and its associated factors.Methods: This is a cross-sectional study conducted on 60 patients with DM. Anthropometric parameters, glycemic control, duration of diabetes and diabetic treatment were collected. Lower and upper...

Objective: Our objective was to determine the relationship between mean blood gamma-GT (GGT) levels and chronic complications of type 2 diabetes.Patients and Methods: This was a descriptive study including 89 diabetic patients followed at the department A of the National Institute of Nutrition in Tunis.Results: The mean age was 56.44 ±13.02 years. The mean GGT level was 54.77±61.13 IU/l. Diabetes was uncontrolled in 93% of ca...

Background: Alteration of gut microbiota leads to increased intestinal permeability, inflammation, and metabolic disorders. The aim of our study was to determine the effect of prebiotic supplementation on glycemic parameters in addition to a weight loss program.Methods: This is an interventional study including 30 obese patients consulting the obesity unit of the Institute of Nutrition in Tunis. The patients were divided into 2 groups matched for age, se...

Background and Aim: Coffee is consumed worldwide and have been an important aspect of societal norms and cultural traditions for centuries. The health effects of routine caffeine consumption and their potential function as modifiable risk factors for cardiovascular disease have recently been the suggested by many studies. The aim of this study is to evaluate the daily caffeine consumption in obese patients and its clinical and metabolic effects.Methods: ...

Background: Sleep is crucial for brain function, productivity, physical and mental well-being. The objective of our work was to examine the relationship between short sleep duration and its associated factors (sociodemographic characteristics, mental health and chronic diseases) in adult individuals with obesity.Methods: Cross sectional study, including 100 obese adult patients consulting the Obesity Unit of the National Institute of Nutrition in Tunis i...

Background: Obese population is at risk of psychological complications such as anxiety and depression. We carried out this study to assess the effect of a weight loss program and prebiotic supplementation on anxiety symptoms and stress levels in an obese adult population.Methods: Interventional study involving 30 obese patients consulting the obesity unit of the National Institute of Nutrition in Tunis between June and August 2022. Patients were divided ...

Background and Aim: Metabolic syndrome (MetS) is a complex disorder that increases the risk of cardiovascular diseases. Neck Circumference (NC) can estimate the subcutaneous upper body fat distribution which has been recognized as associated with MetS. The aim of our study is to investigate the possible association of NC with cardiometabolic risk factors and MetS and to determine the possible cutoff points of NC for the diagnosis of MetS.Methods: This is...

Introduction: The diabetic foot is a frequent complication that can be life-threatening for the diabetic patient. The risk of amputation is multiplied by 40 in the diabetic patient compared to the non-diabetic population. Our aims were to determine the prevalence of foot amputation in patients hospitalized for poorly controlled diabetes, and to determine the risk factors associated with amputation.Method: This is a cross-sectional analytical study, inclu...

Background: The role of gut microbiota on our health is increasingly well known. It plays a role in digestive, metabolic, immune and neurological functions. The objective of our work was to evaluate the effect of prebiotic and probiotic supplementation on the lipid profile in addition of a weight loss program.Methods: This is an interventional study involving 45 obese patients consulting the obesity unit of the Institute of Nutrition of Tunis during the ...

Introduction: Non-alcoholic fatty liver disease (NAFLD) represents the most common and fastest growing liver disease. Its incidence is associated with the global obesity epidemic.Objective: To develop a simple score to predict the risk of NAFLD in the obese patient.Methods and Materials: This is a descriptive cross-sectional study including 95 patients who consulted at the Human Obesity Research Unit of the National Institute of Nu...